Lnk constrains myeloproliferative diseases in mice

Hematopoietic stem and progenitor cell (HSPC) expansion is regulated by intrinsic signaling pathways activated by cytokines. The intracellular kinase JAK2 plays an essential role in cytokine signaling, and activating mutations in JAK2 are found in a number of hematologic malignancies. We previously...

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Main Authors: Bersenev, Alexey, Wu, Chao, Balcerek, Joanna, Jing, Jiang, Kundu, Mondira, Blobel, Gerd A., Chikwava, Kudakwashe R., Tong, Wei
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877957/
https://ncbi.nlm.nih.gov/pubmed/20458146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI42032
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