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LNK/SH2B3 regulates IL-7 receptor signaling in normal and malignant B-progenitors
Philadelphia chromosome–like acute lymphoblastic leukemia (Ph-like ALL) is a high-risk ALL commonly associated with alterations that affect the tyrosine kinase pathway, tumor suppressors, and lymphoid transcription factors. Loss-of-function mutations in the gene-encoding adaptor protein LNK (also kn...
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| Publicado no: | J Clin Invest |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4811117/ https://ncbi.nlm.nih.gov/pubmed/26974155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI81468 |
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