LNK/SH2B3 regulates IL-7 receptor signaling in normal and malignant B-progenitors

Philadelphia chromosome–like acute lymphoblastic leukemia (Ph-like ALL) is a high-risk ALL commonly associated with alterations that affect the tyrosine kinase pathway, tumor suppressors, and lymphoid transcription factors. Loss-of-function mutations in the gene-encoding adaptor protein LNK (also kn...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Cheng, Ying, Chikwava, Kudakwashe, Wu, Chao, Zhang, Haibing, Bhagat, Anchit, Pei, Dehua, Choi, John K., Tong, Wei
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811117/
https://ncbi.nlm.nih.gov/pubmed/26974155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI81468
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