LNK (SH2B3): paradoxical effects in ovarian cancer

LNK (SH2B3) is an adaptor protein studied extensively in normal and malignant hematopoietic cells. In these cells, it down-regulates activated tyrosine kinases at the cell surface resulting in an antiproliferative effect. To date, no studies have examined activities of LNK in solid tumors. In this s...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Ding, Ling-Wen, Sun, Qiao-Yang, Lin, De-Chen, Chien, Wenwen, Hattori, Norimichi, Dong, Xue-Ming, Gery, Sigal, Garg, Manoj, Doan, Ngan B., Said, Jonathan W., Xiao, Jin-Fen, Yang, Henry, Liu, Li-Zhen, Meng, Xuan, Huang, Ruby Yun-Ju, Tang, Kai, Koeffler, H Phillip
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4188804/
https://ncbi.nlm.nih.gov/pubmed/24704825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.34
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