LNK (SH2B3): paradoxical effects in ovarian cancer

LNK (SH2B3) is an adaptor protein studied extensively in normal and malignant hematopoietic cells. In these cells, it down-regulates activated tyrosine kinases at the cell surface resulting in an antiproliferative effect. To date, no studies have examined activities of LNK in solid tumors. In this s...

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Detalhes bibliográficos
Main Authors: Ding, Ling-Wen, Sun, Qiao-Yang, Lin, De-Chen, Chien, Wenwen, Hattori, Norimichi, Dong, Xue-Ming, Gery, Sigal, Garg, Manoj, Doan, Ngan B., Said, Jonathan W., Xiao, Jin-Fen, Yang, Henry, Liu, Li-Zhen, Meng, Xuan, Huang, Ruby Yun-Ju, Tang, Kai, Koeffler, H Phillip
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4188804/
https://ncbi.nlm.nih.gov/pubmed/24704825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.34
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