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Genomic instability in mice is greater in Fanconi anemia caused by deficiency of Fancd2 than Fancg
Fanconi anemia (FA) results from mutations in the FANC genes and is characterized by bone marrow failure, birth defects and a high incidence of cancer. FANCG is a part of the FA core complex that is responsible for monoubiquitination of FANCD2 and FANCI. The precise role of the FA pathway is not wel...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3059244/ https://ncbi.nlm.nih.gov/pubmed/21118969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-1022 |
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