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Fanconi Anemia and the Underlying Causes of Genomic Instability

Fanconi anemia (FA) is a rare genetic disorder, characterized by birth defects, progressive bone marrow failure, and a predisposition to cancer. This devastating disease is caused by germline mutations in any one of the 22 known FA genes, where the gene products are primarily responsible for the res...

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Detalhes bibliográficos
Publicado no:Environ Mol Mutagen
Main Authors: Rageul, Julie, Kim, Hyungjin
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7778457/
https://ncbi.nlm.nih.gov/pubmed/31983075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.22358
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