Structural basis of the fanconi anemia-associated mutations within the FANCA and FANCG complex

Monoubiquitination of the Fanconi anemia complementation group D2 (FANCD2) protein by the FA core ubiquitin ligase complex is the central event in the FA pathway. FANCA and FANCG play major roles in the nuclear localization of the FA core complex. Mutations of these two genes are the most frequently...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Jeong, Eunyoung, Lee, Seong-Gyu, Kim, Hyun-Suk, Yang, Jihyeon, Shin, Jinwoo, Kim, Youngran, Kim, Jihan, Schärer, Orlando D, Kim, Youngjin, Yeo, Jung-Eun, Kim, Ho Min, Cho, Yunje
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
Soggetti:
Structural Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7102982/
https://ncbi.nlm.nih.gov/pubmed/32002546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa062
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