Structural basis of the fanconi anemia-associated mutations within the FANCA and FANCG complex

Monoubiquitination of the Fanconi anemia complementation group D2 (FANCD2) protein by the FA core ubiquitin ligase complex is the central event in the FA pathway. FANCA and FANCG play major roles in the nuclear localization of the FA core complex. Mutations of these two genes are the most frequently...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Jeong, Eunyoung, Lee, Seong-Gyu, Kim, Hyun-Suk, Yang, Jihyeon, Shin, Jinwoo, Kim, Youngran, Kim, Jihan, Schärer, Orlando D, Kim, Youngjin, Yeo, Jung-Eun, Kim, Ho Min, Cho, Yunje
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7102982/
https://ncbi.nlm.nih.gov/pubmed/32002546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa062
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