Structural basis of the fanconi anemia-associated mutations within the FANCA and FANCG complex

Monoubiquitination of the Fanconi anemia complementation group D2 (FANCD2) protein by the FA core ubiquitin ligase complex is the central event in the FA pathway. FANCA and FANCG play major roles in the nuclear localization of the FA core complex. Mutations of these two genes are the most frequently...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Jeong, Eunyoung, Lee, Seong-Gyu, Kim, Hyun-Suk, Yang, Jihyeon, Shin, Jinwoo, Kim, Youngran, Kim, Jihan, Schärer, Orlando D, Kim, Youngjin, Yeo, Jung-Eun, Kim, Ho Min, Cho, Yunje
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Structural Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7102982/
https://ncbi.nlm.nih.gov/pubmed/32002546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa062
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