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The “less-is-more” in therapeutic antibodies: Afucosylated anti-cancer antibodies with enhanced antibody-dependent cellular cytotoxicity
Therapeutic monoclonal antibodies are the fastest growing class of biological therapeutics for the treatment of various cancers and inflammatory disorders. In cancer immunotherapy, some IgG1 antibodies rely on the Fc-mediated immune effector function, antibody-dependent cellular cytotoxicity (ADCC),...
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| Prif Awduron: | , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
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Taylor & Francis
2018
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6150623/ https://ncbi.nlm.nih.gov/pubmed/29733746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2018.1466767 |
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