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Implications of understanding the signaling, cellular, and cytotoxic mechanisms afforded by afucosylated antibodies
Afucosylated antibodies potentiate natural killer (NK) cell-mediated antibody-dependent cellular cytotoxicity (ADCC) by enhancing signaling pathways and cellular processes, which in turn, increases cytotoxic potential. Importantly, a better understanding of these processes and properties will aid in...
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| Publicado no: | Oncoimmunology |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4485832/ https://ncbi.nlm.nih.gov/pubmed/26155429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1009288 |
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