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Natural Killer Cell Mediated Antibody-Dependent Cellular Cytotoxicity in Tumor Immunotherapy with Therapeutic Antibodies

In the last decade several therapeutic antibodies have been Federal Drug Administration (FDA) and European Medicines Agency (EMEA) approved. Although their mechanisms of action in vivo is not fully elucidated, antibody-dependent cellular cytotoxicity (ADCC) mediated by natural killer (NK) cells is p...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Seidel, Ursula J. E., Schlegel, Patrick, Lang, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608903/
https://ncbi.nlm.nih.gov/pubmed/23543707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00076
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