Natural Killer Cell Mediated Antibody-Dependent Cellular Cytotoxicity in Tumor Immunotherapy with Therapeutic Antibodies

In the last decade several therapeutic antibodies have been Federal Drug Administration (FDA) and European Medicines Agency (EMEA) approved. Although their mechanisms of action in vivo is not fully elucidated, antibody-dependent cellular cytotoxicity (ADCC) mediated by natural killer (NK) cells is p...

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Autores principales: Seidel, Ursula J. E., Schlegel, Patrick, Lang, Peter
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2013
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608903/
https://ncbi.nlm.nih.gov/pubmed/23543707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00076
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