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CHO-gmt5, a novel CHO glycosylation mutant for producing afucosylated and asialylated recombinant antibodies
Engineered zinc-finger nucleases (ZFNs) are powerful tools for creating double-stranded-breaks (DSBs) in genomic DNA in a site-specific manner. These DSBs generated by ZFNs can be repaired by homology-directed repair or nonhomologous end joining, in which the latter can be exploited to generate inse...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3609627/ https://ncbi.nlm.nih.gov/pubmed/22989990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/bioe.22262 |
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