Localized Induction of Wild-Type and Mutant Alpha-Synuclein Aggregation Reveals Propagation along Neuroanatomical Tracts

Misfolded alpha-synuclein (αS) may exhibit a number of characteristics similar to those of the prion protein, including the apparent ability to spread along neuroanatomical connections. The demonstration for this mechanism of spread is largely based on the intracerebral injections of preaggregated α...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Ayers, Jacob I., Riffe, Cara J., Sorrentino, Zachary A., Diamond, Jeffrey, Fagerli, Eric, Brooks, Mieu, Galaleldeen, Ahmad, Hart, P. John, Giasson, Benoit I.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2018
Matèries:
Prions
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6146706/
https://ncbi.nlm.nih.gov/pubmed/29976670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00586-18
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