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Demethylator phenotypes in acute myeloid leukemia

Acute myeloid leukemia (AML) often harbors mutations in epigenetic regulators, and also has frequent DNA hypermethylation, including the presence of CpG island methylator phenotypes (CIMP). Although global hypomethylation is well-known in cancer, the question of whether distinct demethylator phenoty...

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Bibliografski detalji
Izdano u:Leukemia
Glavni autori: Kelly, Andrew D., Madzo, Jozef, Madireddi, Priyanka, Kropf, Patricia, Good, Charly R., Jelinek, Jaroslav, Issa, Jean-Pierre J.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6128790/
https://ncbi.nlm.nih.gov/pubmed/29556023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-018-0084-2
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