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Demethylator phenotypes in acute myeloid leukemia

Acute myeloid leukemia (AML) often harbors mutations in epigenetic regulators, and also has frequent DNA hypermethylation, including the presence of CpG island methylator phenotypes (CIMP). Although global hypomethylation is well-known in cancer, the question of whether distinct demethylator phenoty...

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Podrobná bibliografie
Vydáno v:Leukemia
Hlavní autoři: Kelly, Andrew D., Madzo, Jozef, Madireddi, Priyanka, Kropf, Patricia, Good, Charly R., Jelinek, Jaroslav, Issa, Jean-Pierre J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6128790/
https://ncbi.nlm.nih.gov/pubmed/29556023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-018-0084-2
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