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Demethylator phenotypes in acute myeloid leukemia

Acute myeloid leukemia (AML) often harbors mutations in epigenetic regulators, and also has frequent DNA hypermethylation, including the presence of CpG island methylator phenotypes (CIMP). Although global hypomethylation is well-known in cancer, the question of whether distinct demethylator phenoty...

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Detalhes bibliográficos
Publicado no:Leukemia
Main Authors: Kelly, Andrew D., Madzo, Jozef, Madireddi, Priyanka, Kropf, Patricia, Good, Charly R., Jelinek, Jaroslav, Issa, Jean-Pierre J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6128790/
https://ncbi.nlm.nih.gov/pubmed/29556023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-018-0084-2
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