Glucocorticoid receptor recruits to enhancers and drives activation by motif-directed binding

Glucocorticoids are potent steroid hormones that regulate immunity and metabolism by activating the transcription factor (TF) activity of glucocorticoid receptor (GR). Previous models have proposed that DNA binding motifs and sites of chromatin accessibility predetermine GR binding and activity. How...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Genome Res
Egile Nagusiak: McDowell, Ian C., Barrera, Alejandro, D'Ippolito, Anthony M., Vockley, Christopher M., Hong, Linda K., Leichter, Sarah M., Bartelt, Luke C., Majoros, William H., Song, Lingyun, Safi, Alexias, Koçak, D. Dewran, Gersbach, Charles A., Hartemink, Alexander J., Crawford, Gregory E., Engelhardt, Barbara E., Reddy, Timothy E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2018
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120625/
https://ncbi.nlm.nih.gov/pubmed/30097539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.233346.117
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