Glucocorticoid receptor recruits to enhancers and drives activation by motif-directed binding

Glucocorticoids are potent steroid hormones that regulate immunity and metabolism by activating the transcription factor (TF) activity of glucocorticoid receptor (GR). Previous models have proposed that DNA binding motifs and sites of chromatin accessibility predetermine GR binding and activity. How...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Genome Res
मुख्य लेखकों: McDowell, Ian C., Barrera, Alejandro, D'Ippolito, Anthony M., Vockley, Christopher M., Hong, Linda K., Leichter, Sarah M., Bartelt, Luke C., Majoros, William H., Song, Lingyun, Safi, Alexias, Koçak, D. Dewran, Gersbach, Charles A., Hartemink, Alexander J., Crawford, Gregory E., Engelhardt, Barbara E., Reddy, Timothy E.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Cold Spring Harbor Laboratory Press 2018
विषय:
Research
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120625/
https://ncbi.nlm.nih.gov/pubmed/30097539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.233346.117
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