Streptococcal inhibitor of complement (SIC) modulates fibrinolysis and enhances bacterial survival within fibrin clots

Some strains of the bacterial pathogen Streptococcus pyogenes secrete protein SIC (streptococcal inhibitor of complement), including strains of the clinically relevant M1 serotype. SIC neutralizes the effect of a number of antimicrobial proteins/peptides and interferes with the function of the host...

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發表在:J Biol Chem
Main Authors: Frick, Inga-Maria, Shannon, Oonagh, Neumann, Ariane, Karlsson, Christofer, Wikström, Mats, Björck, Lars
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2018
主題:
Microbiology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120194/
https://ncbi.nlm.nih.gov/pubmed/30002122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.001988
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