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Streptococcal protein SIC activates monocytes and induces inflammation

Streptococcus pyogenes is a major bacterial pathogen in the human population and isolates of the clinically important M1 serotype secrete protein Streptococcal inhibitor of complement (SIC) known to interfere with human innate immunity. Here we find that SIC from M1 bacteria interacts with TLR2 and...

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Dades bibliogràfiques
Publicat a:iScience
Autors principals: Neumann, Ariane, Happonen, Lotta, Karlsson, Christofer, Bahnan, Wael, Frick, Inga-Maria, Björck, Lars
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8027542/
https://ncbi.nlm.nih.gov/pubmed/33855284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102339
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