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Streptococcal inhibitor of complement (SIC) modulates fibrinolysis and enhances bacterial survival within fibrin clots

Some strains of the bacterial pathogen Streptococcus pyogenes secrete protein SIC (streptococcal inhibitor of complement), including strains of the clinically relevant M1 serotype. SIC neutralizes the effect of a number of antimicrobial proteins/peptides and interferes with the function of the host...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Frick, Inga-Maria, Shannon, Oonagh, Neumann, Ariane, Karlsson, Christofer, Wikström, Mats, Björck, Lars
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120194/
https://ncbi.nlm.nih.gov/pubmed/30002122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.001988
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