Antibacterial Activity of the Contact and Complement Systems Is Blocked by SIC, a Protein Secreted by Streptococcus pyogenes

Recent studies have shown that activation of complement and contact systems results in the generation of antibacterial peptides. Streptococcus pyogenes, a major bacterial pathogen in humans, exists in >100 different serotypes due to sequence variation in the surface-associated M protein. Cases of...

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Bibliographische Detailangaben
Hauptverfasser: Frick, Inga-Maria, Shannon, Oonagh, Åkesson, Per, Mörgelin, Matthias, Collin, Mattias, Schmidtchen, Artur, Björck, Lars
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Microbiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020741/
https://ncbi.nlm.nih.gov/pubmed/21068386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.178350
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