Streptococcal inhibitor of complement (SIC) modulates fibrinolysis and enhances bacterial survival within fibrin clots

Some strains of the bacterial pathogen Streptococcus pyogenes secrete protein SIC (streptococcal inhibitor of complement), including strains of the clinically relevant M1 serotype. SIC neutralizes the effect of a number of antimicrobial proteins/peptides and interferes with the function of the host...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Frick, Inga-Maria, Shannon, Oonagh, Neumann, Ariane, Karlsson, Christofer, Wikström, Mats, Björck, Lars
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2018
Matèries:
Microbiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120194/
https://ncbi.nlm.nih.gov/pubmed/30002122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.001988
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