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Streptococcal inhibitor of complement (SIC) modulates fibrinolysis and enhances bacterial survival within fibrin clots

Some strains of the bacterial pathogen Streptococcus pyogenes secrete protein SIC (streptococcal inhibitor of complement), including strains of the clinically relevant M1 serotype. SIC neutralizes the effect of a number of antimicrobial proteins/peptides and interferes with the function of the host...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Frick, Inga-Maria, Shannon, Oonagh, Neumann, Ariane, Karlsson, Christofer, Wikström, Mats, Björck, Lars
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120194/
https://ncbi.nlm.nih.gov/pubmed/30002122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.001988
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