Vaccine-induced, but not natural immunity, against the Streptococcal inhibitor of complement protects against invasive disease

Highly pathogenic emm1 Streptococcus pyogenes strains secrete the multidomain Streptococcal inhibitor of complement (SIC) that binds and inactivates components of the innate immune response. We aimed to determine if naturally occurring or vaccine-induced antibodies to SIC are protective against inva...

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Detalhes bibliográficos
Publicado no:NPJ Vaccines
Main Authors: Tan, Lionel K. K., Reglinski, Mark, Teo, Daryl, Reza, Nada, Lamb, Lucy E. M., Nageshwaran, Vaitehi, Turner, Claire E., Wikstrom, Mats, Frick, Inga-Maria, Bjorck, Lars, Sriskandan, Shiranee
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8062509/
https://ncbi.nlm.nih.gov/pubmed/33888727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-021-00326-3
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