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Increased macrophage-derived SPARC precedes collagen deposition in myocardial fibrosis
Myocardial fibrosis and the resultant increases in left ventricular stiffness represent pivotal consequences of chronic pressure overload (PO) that impact both functional capacity and the rates of morbid and mortal events. However, the time course and cellular mechanisms that underlie PO-induced fib...
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| Pubblicato in: | Am J Physiol Heart Circ Physiol |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Physiological Society
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6087775/ https://ncbi.nlm.nih.gov/pubmed/29522370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00719.2017 |
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