Effects of the absence of procollagen C-endopeptidase enhancer-2 on myocardial collagen accumulation in chronic pressure overload

Cardiac interstitial fibrillar collagen accumulation, such as that associated with chronic pressure overload (PO), has been shown to impair left ventricular diastolic function. Therefore, insight into cellular mechanisms that mediate excessive collagen deposition in the myocardium is pivotal to this...

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Autors principals: Baicu, Catalin F., Zhang, Yuhua, Van Laer, An O., Renaud, Ludivine, Zile, Michael R., Bradshaw, Amy D.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2012
Matèries:
Integrative Cardiovascular Physiology and Pathophysiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404697/
https://ncbi.nlm.nih.gov/pubmed/22610170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00227.2012
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