Cardiac-restricted overexpression or deletion of tissue inhibitor of matrix metalloproteinase-4: differential effects on left ventricular structure and function following pressure overload-induced hypertrophy

Historically, the tissue inhibitors of matrix metalloproteinases (TIMPs) were considered monochromatic in function. However, differential TIMP profiles more recently observed with left ventricular (LV) dysfunction and matrix remodeling suggest more diverse biological roles for individual TIMPs. This...

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Detalhes bibliográficos
Main Authors: Yarbrough, William M., Baicu, Catalin, Mukherjee, Rupak, Van Laer, An, Rivers, William T., McKinney, Richard A., Prescott, Corey B., Stroud, Robert E., Freels, Parker D., Zellars, Kia N., Zile, Michael R., Spinale, Francis G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Integrative Cardiovascular Physiology and Pathophysiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187400/
https://ncbi.nlm.nih.gov/pubmed/24993046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00063.2014
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