Cardiac-restricted overexpression or deletion of tissue inhibitor of matrix metalloproteinase-4: differential effects on left ventricular structure and function following pressure overload-induced hypertrophy

Historically, the tissue inhibitors of matrix metalloproteinases (TIMPs) were considered monochromatic in function. However, differential TIMP profiles more recently observed with left ventricular (LV) dysfunction and matrix remodeling suggest more diverse biological roles for individual TIMPs. This...

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Détails bibliographiques
Auteurs principaux: Yarbrough, William M., Baicu, Catalin, Mukherjee, Rupak, Van Laer, An, Rivers, William T., McKinney, Richard A., Prescott, Corey B., Stroud, Robert E., Freels, Parker D., Zellars, Kia N., Zile, Michael R., Spinale, Francis G.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2014
Sujets:
Integrative Cardiovascular Physiology and Pathophysiology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187400/
https://ncbi.nlm.nih.gov/pubmed/24993046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00063.2014
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