Cardiac-restricted overexpression or deletion of tissue inhibitor of matrix metalloproteinase-4: differential effects on left ventricular structure and function following pressure overload-induced hypertrophy

Historically, the tissue inhibitors of matrix metalloproteinases (TIMPs) were considered monochromatic in function. However, differential TIMP profiles more recently observed with left ventricular (LV) dysfunction and matrix remodeling suggest more diverse biological roles for individual TIMPs. This...

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Bibliographische Detailangaben
Hauptverfasser: Yarbrough, William M., Baicu, Catalin, Mukherjee, Rupak, Van Laer, An, Rivers, William T., McKinney, Richard A., Prescott, Corey B., Stroud, Robert E., Freels, Parker D., Zellars, Kia N., Zile, Michael R., Spinale, Francis G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2014
Schlagworte:
Integrative Cardiovascular Physiology and Pathophysiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187400/
https://ncbi.nlm.nih.gov/pubmed/24993046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00063.2014
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