Cardiac-restricted overexpression or deletion of tissue inhibitor of matrix metalloproteinase-4: differential effects on left ventricular structure and function following pressure overload-induced hypertrophy

Historically, the tissue inhibitors of matrix metalloproteinases (TIMPs) were considered monochromatic in function. However, differential TIMP profiles more recently observed with left ventricular (LV) dysfunction and matrix remodeling suggest more diverse biological roles for individual TIMPs. This...

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Main Authors: Yarbrough, William M., Baicu, Catalin, Mukherjee, Rupak, Van Laer, An, Rivers, William T., McKinney, Richard A., Prescott, Corey B., Stroud, Robert E., Freels, Parker D., Zellars, Kia N., Zile, Michael R., Spinale, Francis G.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2014
Teme:
Integrative Cardiovascular Physiology and Pathophysiology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187400/
https://ncbi.nlm.nih.gov/pubmed/24993046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00063.2014
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