Direct regulation of membrane type 1 matrix metalloproteinase following myocardial infarction causes changes in survival, cardiac function, and remodeling

The membrane type 1 matrix metalloproteinase (MT1-MMP) is increased in left ventricular (LV) failure. However, the direct effects of altered MT1-MMP levels on survival, LV function, and geometry following myocardial infarction (MI) and the proteolytic substrates involved in this process remain uncle...

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Autors principals: Zavadzkas, Juozas A., Mukherjee, Rupak, Rivers, William T., Patel, Risha K., Meyer, Evan C., Black, Laurel E., McKinney, Richard A., Oelsen, J. Marshall, Stroud, Robert E., Spinale, Francis G.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2011
Matèries:
Integrative Cardiovascular Physiology and Pathophysiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197432/
https://ncbi.nlm.nih.gov/pubmed/21666120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00141.2011
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