Targeted Overexpression of Tissue Inhibitor of Matrix Metalloproteinase-4 Modifies Post Myocardial Infarction Remodeling in Mice

RATIONALE: Myocardial infarction (MI) causes an imbalance between matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs (TIMPs) and is associated with adverse LV remodeling. A uniform reduction in TIMP-4 post-MI has been observed. OBJECTIVE: Examine post-MI remodeling with cardiac restricte...

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Главные авторы: Zavadzkas, Juozas A., Stroud, Robert E., Bouges, Shenikqua, Mukherjee, Rupak, Jones, Jeffrey R., Patel, Risha K., McDermott, Paul J., Spinale, Francis G.
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040980/
https://ncbi.nlm.nih.gov/pubmed/24637197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.114.303634
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