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Mechanistic Relationship Between MT1-MMP and the Myocardial Response to Pressure-Overload

BACKGROUND: While matrix metalloproteinases (MMPs) were initially thought to primarily result in extracellular matrix degradation, certain MMP types such as membrane type-1 MMP (MT1-MMP) may also be involved in profibrotic cascades through hydrolysis of latency-associated transforming growth factor...

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Bibliografske podrobnosti
Main Authors: Zile, Michael R., Baicu, Catalin F., Stroud, Robert E., Van Laer, An O., Jones, Jeffrey A., Patel, Risha, Mukherjee, Rupak, Spinale, Francis G.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961496/
https://ncbi.nlm.nih.gov/pubmed/24395927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.113.000984
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