Effects of the absence of procollagen C-endopeptidase enhancer-2 on myocardial collagen accumulation in chronic pressure overload

Cardiac interstitial fibrillar collagen accumulation, such as that associated with chronic pressure overload (PO), has been shown to impair left ventricular diastolic function. Therefore, insight into cellular mechanisms that mediate excessive collagen deposition in the myocardium is pivotal to this...

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Main Authors: Baicu, Catalin F., Zhang, Yuhua, Van Laer, An O., Renaud, Ludivine, Zile, Michael R., Bradshaw, Amy D.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2012
Teme:
Integrative Cardiovascular Physiology and Pathophysiology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404697/
https://ncbi.nlm.nih.gov/pubmed/22610170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00227.2012
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