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Increased ADAMTS1 mediates SPARC-dependent collagen deposition in the aging myocardium
Secreted protein acidic and rich in cysteine (SPARC) is a collagen-binding matricellular protein highly expressed during fibrosis. Fibrosis is a prominent component of cardiac aging that reduces myocardial elasticity. Previously, we reported that SPARC deletion attenuated myocardial stiffness and co...
में बचाया:
| में प्रकाशित: | Am J Physiol Endocrinol Metab |
|---|---|
| मुख्य लेखकों: | , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
American Physiological Society
2016
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4935141/ https://ncbi.nlm.nih.gov/pubmed/27143554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00040.2016 |
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