Scalable synthesis and validation of PAMAM dendrimer‐N‐acetyl cysteine conjugate for potential translation

Dendrimer‐N‐acetyl cysteine (D‐NAC) conjugate has shown significant promise in multiple preclinical models of brain injury and is undergoing clinical translation. D‐NAC is a generation‐4 hydroxyl‐polyamidoamine dendrimer conjugate where N‐acetyl cysteine (NAC) is covalently bound through disulfide l...

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Detaylı Bibliyografya
Yayımlandı:Bioeng Transl Med
Asıl Yazarlar: Sharma, Rishi, Sharma, Anjali, Kambhampati, Siva P., Reddy, Rajsekar Rami, Zhang, Zhi, Cleland, Jeffrey L., Kannan, Sujatha, Kannan, Rangaramanujam M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2018
Konular:
Research Reports
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063872/
https://ncbi.nlm.nih.gov/pubmed/30065965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/btm2.10094
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