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Dendrimer–N-Acetyl-L-Cysteine Modulates Monophagocytic Response in Adrenoleukodystrophy

OBJECTIVE: X-linked adrenoleukodystrophy (ALD) is a neurodegenerative disorder due to mutations in the peroxisomal very long-chain fatty acyl-CoA transporter, ABCD1, with limited therapeutic options. ALD may manifest in a slowly progressive adrenomyeloneuropathy (AMN) phenotype, or switch to rapid i...

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Detalhes bibliográficos
Publicado no:Ann Neurol
Main Authors: Turk, Bela R., Nemeth, Christina L., Marx, Joel S., Tiffany, Carol, Jones, Richard, Theisen, Benjamin, Kambhampati, Siva, Ramireddy, Raj, Singh, Sarabdeep, Rosen, Melissa, Kaufman, Miriam L., Murray, Connor F., Watkins, Paul A., Kannan, Sujatha, Kannan, Rangaramanujam, Fatemi, Ali
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6454885/
https://ncbi.nlm.nih.gov/pubmed/30069915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.25303
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