Dendrimer–N-Acetyl-L-Cysteine Modulates Monophagocytic Response in Adrenoleukodystrophy

OBJECTIVE: X-linked adrenoleukodystrophy (ALD) is a neurodegenerative disorder due to mutations in the peroxisomal very long-chain fatty acyl-CoA transporter, ABCD1, with limited therapeutic options. ALD may manifest in a slowly progressive adrenomyeloneuropathy (AMN) phenotype, or switch to rapid i...

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Gepubliceerd in:Ann Neurol
Hoofdauteurs: Turk, Bela R., Nemeth, Christina L., Marx, Joel S., Tiffany, Carol, Jones, Richard, Theisen, Benjamin, Kambhampati, Siva, Ramireddy, Raj, Singh, Sarabdeep, Rosen, Melissa, Kaufman, Miriam L., Murray, Connor F., Watkins, Paul A., Kannan, Sujatha, Kannan, Rangaramanujam, Fatemi, Ali
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6454885/
https://ncbi.nlm.nih.gov/pubmed/30069915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.25303
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