Dendrimer-mediated delivery of N-acetyl cysteine to microglia in a mouse model of Rett syndrome

BACKGROUND: Rett syndrome (RTT) is a pervasive developmental disorder that is progressive and has no effective cure. Immune dysregulation, oxidative stress, and excess glutamate in the brain mediated by glial dysfunction have been implicated in the pathogenesis and worsening of symptoms of RTT. In t...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Nance, Elizabeth, Kambhampati, Siva P., Smith, Elizabeth S., Zhang, Zhi, Zhang, Fan, Singh, Sarabdeep, Johnston, Michael V., Rangaramanujam, Kannan, Blue, Mary E., Kannan, Sujatha
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5735803/
https://ncbi.nlm.nih.gov/pubmed/29258545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-1004-5
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