Dendrimer-mediated delivery of N-acetyl cysteine to microglia in a mouse model of Rett syndrome

BACKGROUND: Rett syndrome (RTT) is a pervasive developmental disorder that is progressive and has no effective cure. Immune dysregulation, oxidative stress, and excess glutamate in the brain mediated by glial dysfunction have been implicated in the pathogenesis and worsening of symptoms of RTT. In t...

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Détails bibliographiques
Publié dans:J Neuroinflammation
Auteurs principaux: Nance, Elizabeth, Kambhampati, Siva P., Smith, Elizabeth S., Zhang, Zhi, Zhang, Fan, Singh, Sarabdeep, Johnston, Michael V., Rangaramanujam, Kannan, Blue, Mary E., Kannan, Sujatha
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5735803/
https://ncbi.nlm.nih.gov/pubmed/29258545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-1004-5
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