Dendrimer-mediated delivery of N-acetyl cysteine to microglia in a mouse model of Rett syndrome

BACKGROUND: Rett syndrome (RTT) is a pervasive developmental disorder that is progressive and has no effective cure. Immune dysregulation, oxidative stress, and excess glutamate in the brain mediated by glial dysfunction have been implicated in the pathogenesis and worsening of symptoms of RTT. In t...

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Foilsithe in:J Neuroinflammation
Main Authors: Nance, Elizabeth, Kambhampati, Siva P., Smith, Elizabeth S., Zhang, Zhi, Zhang, Fan, Singh, Sarabdeep, Johnston, Michael V., Rangaramanujam, Kannan, Blue, Mary E., Kannan, Sujatha
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2017
Ábhair:
Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5735803/
https://ncbi.nlm.nih.gov/pubmed/29258545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-1004-5
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