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Glutathione boosting the cytotoxicity of a magnetic platinum(iv) nano-prodrug in tumor cells
Superparamagnetic iron oxide nanoparticles (SPIONs) are potential vehicles for targeted drug delivery and viable contrast agents for magnetic resonance imaging (MRI). A Pt(IV) prodrug (HSPt) derived from functionalization of cisplatin with hydroxyl and succinate is conjugated with a poly(ethylene gl...
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| Publié dans: | Chem Sci |
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| Auteurs principaux: | , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Royal Society of Chemistry
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6054038/ https://ncbi.nlm.nih.gov/pubmed/30090279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc04049c |
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