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Mitochondrion-targeted platinum complexes suppressing lung cancer through multiple pathways involving energy metabolism
Mitochondria are potential therapeutic targets for anticancer drugs. A series of mitochondrion-targeted monofunctional platinum complexes, [Pt(ortho-PPh(3)CH(2)Py)(NH(3))(2)Cl](NO(3))(2) (OPT), [Pt(meta-PPh(3)CH(2)Py)(NH(3))(2)Cl](NO(3))(2) (MPT), and [Pt(para-PPh(3)CH(2)Py)(NH(3))(2)Cl](NO(3))(2) (...
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| Publié dans: | Chem Sci |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Royal Society of Chemistry
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6428137/ https://ncbi.nlm.nih.gov/pubmed/30996891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc04871a |
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