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Mitochondrion-targeted platinum complexes suppressing lung cancer through multiple pathways involving energy metabolism

Mitochondria are potential therapeutic targets for anticancer drugs. A series of mitochondrion-targeted monofunctional platinum complexes, [Pt(ortho-PPh(3)CH(2)Py)(NH(3))(2)Cl](NO(3))(2) (OPT), [Pt(meta-PPh(3)CH(2)Py)(NH(3))(2)Cl](NO(3))(2) (MPT), and [Pt(para-PPh(3)CH(2)Py)(NH(3))(2)Cl](NO(3))(2) (...

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Dades bibliogràfiques
Publicat a:Chem Sci
Autors principals: Zhu, Zhenzhu, Wang, Zenghui, Zhang, Changli, Wang, Yanjun, Zhang, Hongmei, Gan, Zhenji, Guo, Zijian, Wang, Xiaoyong
Format: Artigo
Idioma:Inglês
Publicat: Royal Society of Chemistry 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428137/
https://ncbi.nlm.nih.gov/pubmed/30996891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc04871a
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