Novel mitochondrion‐targeting copper(II) complex induces HK2 malfunction and inhibits glycolysis via Drp1‐mediating mitophagy in HCC

[Cu(ttpy‐tpp)Br(2)]Br (abbreviated as CTB) is a novel mitochondrion‐targeting copper(II) complex synthesized by our research group, which contains tri‐phenyl‐phosphonium (TPP) groups as its lipophilic property. In this study, we explored how CTB affects mitochondrial functions and exerts its anti‐tu...

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Bibliografske podrobnosti
izdano v:J Cell Mol Med
Main Authors: Li, Mengmeng, Shao, Jiangjuan, Guo, Zijian, Jin, Chun, Wang, Ling, Wang, Feixia, Jia, Yan, Zhu, Zhenzhu, Zhang, Ziji, Zhang, Feng, Zheng, Shizhong, Wang, Xiaoyong
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7077532/
https://ncbi.nlm.nih.gov/pubmed/31994339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14971
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