Novel mitochondrion‐targeting copper(II) complex induces HK2 malfunction and inhibits glycolysis via Drp1‐mediating mitophagy in HCC

[Cu(ttpy‐tpp)Br(2)]Br (abbreviated as CTB) is a novel mitochondrion‐targeting copper(II) complex synthesized by our research group, which contains tri‐phenyl‐phosphonium (TPP) groups as its lipophilic property. In this study, we explored how CTB affects mitochondrial functions and exerts its anti‐tu...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Li, Mengmeng, Shao, Jiangjuan, Guo, Zijian, Jin, Chun, Wang, Ling, Wang, Feixia, Jia, Yan, Zhu, Zhenzhu, Zhang, Ziji, Zhang, Feng, Zheng, Shizhong, Wang, Xiaoyong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7077532/
https://ncbi.nlm.nih.gov/pubmed/31994339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14971
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