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Novel copper complex CTB regulates methionine cycle induced TERT hypomethylation to promote HCC cells senescence via mitochondrial SLC25A26

Related research has recognized the vital role of methionine cycle metabolism in cancers. However, the role and mechanism of methionine cycle metabolism in hepatocellular carcinoma are still unknown. In this study, we found that [Cu(ttpy-tpp)Br(2)]Br (Referred to as CTB) could induce hepatocellular...

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Dettagli Bibliografici
Pubblicato in:Cell Death Dis
Autori principali: Jin, Chun, Li, Yujia, Su, Ying, Guo, Zijian, Wang, Xiaoyong, Wang, Shijun, Zhang, Feng, Zhang, Zili, Shao, Jiangjuan, Zheng, Shizhong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7548283/
https://ncbi.nlm.nih.gov/pubmed/33041323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03048-x
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