Novel copper complex CTB regulates methionine cycle induced TERT hypomethylation to promote HCC cells senescence via mitochondrial SLC25A26

Related research has recognized the vital role of methionine cycle metabolism in cancers. However, the role and mechanism of methionine cycle metabolism in hepatocellular carcinoma are still unknown. In this study, we found that [Cu(ttpy-tpp)Br(2)]Br (Referred to as CTB) could induce hepatocellular...

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Detaylı Bibliyografya
Yayımlandı:Cell Death Dis
Asıl Yazarlar: Jin, Chun, Li, Yujia, Su, Ying, Guo, Zijian, Wang, Xiaoyong, Wang, Shijun, Zhang, Feng, Zhang, Zili, Shao, Jiangjuan, Zheng, Shizhong
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7548283/
https://ncbi.nlm.nih.gov/pubmed/33041323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03048-x
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