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Novel copper complex CTB regulates methionine cycle induced TERT hypomethylation to promote HCC cells senescence via mitochondrial SLC25A26

Related research has recognized the vital role of methionine cycle metabolism in cancers. However, the role and mechanism of methionine cycle metabolism in hepatocellular carcinoma are still unknown. In this study, we found that [Cu(ttpy-tpp)Br(2)]Br (Referred to as CTB) could induce hepatocellular...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Jin, Chun, Li, Yujia, Su, Ying, Guo, Zijian, Wang, Xiaoyong, Wang, Shijun, Zhang, Feng, Zhang, Zili, Shao, Jiangjuan, Zheng, Shizhong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7548283/
https://ncbi.nlm.nih.gov/pubmed/33041323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03048-x
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