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Induction of targeted necrosis with HER2-targeted platinum(iv) anticancer prodrugs

It is well-recognized that the failure of many chemotherapeutics arises due to an inability to induce apoptosis. Most cancers acquire a myriad of pro-survival adaptations, and the vast heterogeneity and accumulation of multiple often unrelated anti-apoptotic signaling pathways have been a major stum...

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Bibliografske podrobnosti
izdano v:Chem Sci
Main Authors: Wong, Daniel Yuan Qiang, Lim, Jun Han, Ang, Wee Han
Format: Artigo
Jezik:Inglês
Izdano: Royal Society of Chemistry 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5490001/
https://ncbi.nlm.nih.gov/pubmed/28706680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc00015g
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