Cell-permeable lanthanide–platinum(iv) anti-cancer prodrugs

Platinum compounds are a vital part of our anti-cancer arsenal, and determining the location and speciation of platinum compounds is crucial. We have synthesised a lanthanide complex bearing a salicylic group (Ln = Gd, Eu) which demonstrates excellent cellular accumulation and minimal cytotoxicity....

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Detalhes bibliográficos
Publicado no:Dalton Trans
Main Authors: Yao, Kezi, Karunanithy, Gogulan, Howarth, Alison, Holdship, Philip, Thompson, Amber L., Christensen, Kirsten E., Baldwin, Andrew J., Faulkner, Stephen, Farrer, Nicola J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society of Chemistry 2021
Assuntos:
Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8237448/
https://ncbi.nlm.nih.gov/pubmed/34080595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d1dt01688a
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